The CD49e antigen is the 160 kDa integrin α5-chain, which is composed of a heavy chain (135 kDa) and a light chain (25 kDa), linked by a disulfide bond. CD49e is non-covalently associated with the 130 kDa integrin β1-chain (CD29 molecule), forming the VLA-5 complex. CD49e is expressed by monocytes, platelets and two myeloid cell lines (U937, K562). It is known as the fibronectin and invasin receptor. It is useful for basic studies of fibronectin-mediated adhesion.
Технические характеристики
| Target Species | Human |
| Specificity | CD49e |
| Other Names | CD49e, Integrin alpha 5 chain, Integrin α5-chain, VLA-5, VLA-alpha5-chain |
| Fluorochrome | FITC |
| Regulatory Status | ASR |
| Size | 2 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | SAM1 |
| Isotype | IgG2b Mouse |
