The CD29 antigen is the 130 kDa integrin β1 chain which is expressed as a heterodimer, non-covalently associated with the integrin α subunits 1 to 6 (CD49a to CD49f) also known as Very Late Antigens (VLA). CD29 is also known as platelet GPIIa. The antigen mediates cellular adhesion and has broad cellular reactivity, but is not expressed by erythrocytes. In normal peripheral blood it is found on a subset of CD4+ and CD8+ T lymphocytes, on a minority of B lymphocytes and on monocytes. The «inducer» subpopulation of CD4+ lymphocytes co-expresses CD4 and CD29.
Технические характеристики
| Target Species | Human |
| Specificity | CD29 |
| Other Names | CD29, gpIIa, integrin beta1 chain, integrin B,1-chain, platelet GPIIa, VLA B chain |
| Fluorochrome | FITC |
| Regulatory Status | ASR |
| Size | 2 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | K20 |
| Isotype | IgG2a Mouse |
| Clone Description | K20 is a non blocking monoclonal antibody in CD29 mediated adhesion. |
| Cross Reactivity | Bovine, Caprine, Porcine, Equine, Canine, Mink |
