The CD2 antigen (LFA-2) is a monomeric 50 kDa glycoprotein. It was formerly described as the sheep red blood cell receptor, causing T-cell rosetting, and has been identified as the ligand for CD58 (LFA-3). It is also a receptor for CD48, CD59 and CD15, which binds to the multimeric form of CD2. CD2 is present on the majority of normal human peripheral blood T lymphocytes and a high percentage of NK cells. It is also expressed by all thymocytes.
Технические характеристики
| Target Species | Human |
| Specificity | CD2 |
| Other Names | CD2, CD58 Ligand, LFA-2, Sheep red blood cell rosettes |
| Fluorochrome | RD1 |
| Regulatory Status | IVD, CE, Japan IVD |
| Size | 100 Tests |
| Format | Liquid |
| Flow Product Line | coulter clone |
| Clone | SFCI3Pt2H9 |
| Isotype | IgG1 Mouse |
| Clone Description | SFCI3Pt2H9 inhibits sheep erythrocyte rosette formation. It has been used as a CD2 reference monoclonal antibody during HLDA 6 (ref.6T-CD2.6). |
| Cross Reactivity | Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Olive Baboon, Common Marmoset, Capuchin Monkey, Squirrel Monkey |
