The CD154 antigen (CD40-ligand), also known as TRAP (Tumor necrosis factor Related Activation Protein), is a member of the Tumor Necrosis Factor (TNF) superfamily. It is a 32 kDa type II transmembrane molecule. CD154 molecule is induced on the surface of activated T cells, mainly on CD4+ T lymphocytes. This ligand for the CD40 molecule is present on some basophils and mast cells. It has critical regulatory roles in T- and B-lymphocyte function.
Технические характеристики
| Target Species | Human |
| Specificity | CD154 |
| Other Names | CD154, CD40 Ligand, CD40L, T-BAM, TNF-related activation protein 1, TRAP |
| Fluorochrome | PE |
| Regulatory Status | ASR |
| Size | 2 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | TRAP-1 |
| Isotype | IgG1 Mouse |
| Clone Description | The TRAP-1 antibody inhibits activation induced by full-length soluble human CD154. |
| Cross Reactivity | Cynomolgus Monkey, Hamadyras Baboon, Indian Rhesus, Olive Baboon |
