The Thrombin Receptor (60 to 80 kDa) is expressed on a variety of cells including platelets and endothelium. The receptor is a substrate of thrombin and has been shown to play a role in the activation of platelets.
Технические характеристики
| Target Species | Human |
| Specificity | Thrombin receptor |
| Other Names | Thrombin, Thrombin receptor |
| Fluorochrome | PE |
| Regulatory Status | ASR |
| Size | 2 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | SPAN 12 |
| Isotype | IgG1 Mouse |
| Clone Description | The SPAN 12 antibody recognizes an epitope on the receptor that spans the thrombin cleavage site. It binds to intact receptors, but not to cleaved ones. SPAN 12 inhibits thrombin-induced receptor activation at reduced thrombin concentrations. |
