Interleukin-2 (IL-2) is a 15-17 kDa cytokine produced and secreted by T cells. The induction of IL-2 secretion is the first step in T cell activation. IL-2 is the major autocrine growth factor for activated T cells and is obligatory for the generation of cytotoxic T cells. IL-2 also promotes the proliferation and the differentiation of NK precursors, B cells and monocytes. Activated CD4+ T cells of the Th1 phenotype produce predominantly IL-2 and Interferon-γ, whereas CD4+ T cells of the Th2 phenotype produce IL-4 and IL-10.
Технические характеристики
| Target Species | Human |
| Specificity | IL-2 |
| Fluorochrome | FITC |
| Regulatory Status | ASR |
| Size | 1 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | IL2.39.1 |
| Isotype | IgG1 Mouse |
