Along with CD8α, the CD8β polypeptide molecule is one of the two chains which can be expressed within the CD8 dimer. CD8α is required for surface expression of CD8β. The α and β glycoproteins have similar molecular weights of 32-34 kDa each. The CD8α/β heterodimer is expressed by TCR α/β+ CD8+ T cells whereas TCR γ/δ+ CD8+ T cells and CD8+ NK cells exclusively express the CD8α/α homodimer.
Технические характеристики
| Target Species | Human |
| Specificity | CD8β |
| Fluorochrome | ECD |
| Regulatory Status | RUO |
| Size | 100 Tests |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | 2ST8.5H7 |
| Isotype | IgG2a Mouse |
| Clone Description | The 2ST8.5H7 monoclonal antibody reacts with an epitope formed by the combination of the α and B polypeptides. |
