The CD71 antigen is known as the transferrin receptor. It mediates cellular iron uptake via internalization and recycling. It is a type II membrane glycoprotein, characterized as a disulfide-bound dimer of two identical subunits of 95 kDa each. CD71 is expressed on activated T and B lymphocytes, macrophages and erythroblasts. The N-Terminal, intracytoplasmic domain of CD71 mediates rapid endocytosis and self recycling. CD71 is absent from resting blood leucocytes. Its expression is upregulated on proliferating cells.
Технические характеристики
| Target Species | Human |
| Specificity | CD71 |
| Other Names | CD71, T9, Transferrin receptor |
| Fluorochrome | PE |
| Regulatory Status | ASR |
| Size | 2 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | YDJ1.2.2 |
| Isotype | IgG1 Mouse |
| Cross Reactivity | Cynomolgus Monkey |
