The CD64 antigen (FcγRI) is a glycoprotein with a molecular weight of 72 kDa. It belongs to the Ig superfamily, consisting of three C2-like Ig domains. It is the high affinity receptor for IgG and is able to bind monomeric human IgG1 and IgG3. This antigen is expressed on macrophages and monocytes. It is also expressed on neutrophils when induced with interferon γ (IFN-γ) and granulocyte colony-stimulating factor (G-CSF).
Технические характеристики
| Target Species | Human |
| Specificity | CD64 |
| Other Names | CD64, FcgammaR1, FcgR1, FcγRI, High affinity IgG receptor |
| Fluorochrome | PC5 |
| Regulatory Status | ASR |
| Size | 1 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | 22 |
| Isotype | IgG1 Mouse |
| Clone Description | The 22 antibody shows especially high affinity binding to human mononuclear phagocytes. The epitope recognized by this antibody is disctinct from the IgG binding site. |
| Cross Reactivity | Indian Rhesus |
