The CD62L antigen, also called LECAM-1, L-selectin or LAM-1, is a 75 kDa molecule. It acts as the peripheral lymph node homing receptor. It is also involved in lymphocyte binding to High Endothelial Venules (HEV) and in lymphocyte rolling on activated endothelium. CD62L is expressed by B and T lymphocytes, monocytes, neutrophils, eosinophils, and approximately half of the peripheral NK lymphocytes. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.
Технические характеристики
| Target Species | Human |
| Specificity | CD62L |
| Other Names | CD62L, LAM-1, LECAM-1, L-selectin |
| Fluorochrome | Pacific Blue* |
| Regulatory Status | ASR |
| Size | 0.5 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | DREG56 |
| Isotype | IgG1 Mouse |
| Clone Description | In contrast to other antibodies recognizing this molecule, DREG56 is particularly effective in blocking CD62L mediated lymphocyte binding to lymph node HEV. DREG56 (ref.33) was used as a CD62L reference monoclonal antibody during the HLDA 6. |
| Cross Reactivity | Bovine, Chimpanzee |
