The CD57 antigen (HNK-1 antigen carbohydrate moiety) is an oligosaccharide with sulfated glucoronic acid residues that may be linked to a variety of polypeptides or lipids. In peripheral blood, it is found on a subset of cells with natural killer activity. It is confined to mononuclear cells, primarily large granular lymphocytes. Many of these CD57+ cells co-express the CD8 antigen and are a subset of the suppressor / cytotoxic T lymphocytes. Cord blood T cells or NK cells lack the CD57 antigen. It is not expressed on red blood cells or on platelets but is present on some neuroectodermal tissues.
Технические характеристики
| Target Species | Human |
| Specificity | CD57 |
| Other Names | CD57, HNK-1 |
| Fluorochrome | FITC |
| Regulatory Status | ASR, Japan IVD |
| Size | 2 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | NC1 |
| Isotype | IgM Mouse |
