The CD56 antigen is a 140 kDa isoform of the Neural Cell Adhesion Molecule (N-CAM). Post-translational modifications to the polypeptide include N- and O- glycosylations, acylation, sulphation and phosphorylation. The different N-CAM isoforms have molecular weights ranging from 135 to 220 kDa. The CD56 antigen is moderately expressed on a subpopulation of peripheral blood large granular lymphocytes and on all cells with NK activity. It is also expressed by subsets of T lymphocytes. CD56 antibodies do not react with granulocytes, monocytes or B cells.
Технические характеристики
| Target Species | Human |
| Specificity | CD56 |
| Other Names | CD56, NCAM, N-CAM, Neural cell adhesion molecule, NKH-1 |
| Fluorochrome | RD1 |
| Regulatory Status | ASR, Japan IVD |
| Size | 0.5 mL |
| Format | Liquid |
| Flow Product Line | coulter clone |
| Clone | N901 |
| Isotype | IgG1 Mouse |
| Clone Description | The N901 (NKH-1) antibody was used as a CD56 reference mAb during HLDA 6. |
| Cross Reactivity | Hamadyras Baboon |
