The CD5 antigen is a single-chain transmembrane glycoprotein with a molecular weight of 67 kDa. The extracellular domain consists of 3 scavenger receptor cysteine-rich (SRCR) domains of approximately 100 amino acids each. CD5 is found on all mature T lymphocytes and on most thymocytes. CD5 is also present on a B lymphocyte subset but is not found on granulocytes or monocytes. CD5 is a ligand for the CD72 antigen, which is present on B lymphocytes. The CD5+ B lymphocyte subset (known as B-1a lymphocytes) may arise from a non-conventional B lineage (independent of bone marrow).
Технические характеристики
| Target Species | Human |
| Specificity | CD5 |
| Other Names | CD5, CD72 Ligand, T1, Tp67 |
| Fluorochrome | PC5 |
| Regulatory Status | ASR |
| Size | 1 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | BL1a |
| Isotype | IgG2a Mouse |
| Clone Description | BL1a monoclonal antibody (ref. 6T-CD5.5) was used as a CD5 reference monoclonal antibody during HLDA/6. |
| Cross Reactivity | Bovine, Equine |
