The CD44 antigens are transmembrane glycoproteins and members of the hyaladherin family of hyaluronan-binding proteins. Multiple CD44 isoforms have been described, the predominant form being CD44S, a glycoprotein of 85 kDa. CD44 is present on most cells or tissues, but not on platelets, hepatocytes, cardiac muscle, kidney tubular epithelium, testis and skin portions. The human blood group antigens Ina/b reside on CD44.
Технические характеристики
| Target Species | Human |
| Specificity | CD44 |
| Other Names | CD44, ECMR-III, gp80-95, H-CAM, Hermes antigen, HUTCH-I, Pgp-1 |
| Fluorochrome | PE |
| Regulatory Status | ASR |
| Size | 2 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | J.173 |
| Isotype | IgG1 Mouse |
| Clone Description | J.173 antibody does not inhibit the binding of hyaluronate to its receptor. It can trigger IL-2-dependent proliferation and cytotoxicity of human T cell clones in vitro. |
| Cross Reactivity | Cynomolgus Monkey, Indian Rhesus, Olive Baboon |
