The CD43 antigen is a 95-135 kDa heavily O-glycosylated and sialylated single chain membrane glycoprotein. This cell surface mucin-type glycoprotein is also called leukosialin or sialophorin. CD43 antigen is expressed by platelets and by all leucocytes, weakly on resting B lymphocytes but highly after activation. A soluble form of CD43 (galactoglycoprotein) can be detected in plasma. This form is produced by proteolytic shedding of the extracellular portion of the membrane molecule after cell activation.
Технические характеристики
| Target Species | Human |
| Specificity | CD43 |
| Other Names | CD43, gp95, gpL115, leukocyte sialoglycoprotein, Leukosialin, sialophorin |
| Fluorochrome | PE |
| Regulatory Status | ASR |
| Size | 2 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | DFT1 |
| Isotype | IgG1 Mouse |
| Clone Description | The DFT1 antibody reacts with an extracellular epitope of the CD43 antigen. It is useful for detecting leucocytes by flow cytometry and immunohistochemistry on routinely-fixed and parrafin-embedded tissue sections. The DFT1 antibody is also able to induce homotypic adhesion of leucocytes. |
| Cross Reactivity | Cynomolgus Monkey, Indian Rhesus, Olive Baboon, Ovine |
