CD305, also called LAIR1 (Leucocyte-associated Ig-like receptor 1), is a 31 kDa type 1 transmembrane molecule with a single N terminal extracellular Ig superfamily C2 domain. The extracellular domain contains one N-glycosylation site. CD305 is expressed on the majority of lymphocytes, NK cells, monocytes, dendritic cells and naïve B cells. It inhibits cell cytotoxicity, cell activation, proliferation and differentiation by phosphorylation of its cytoplasmic ITIM motifs.
Технические характеристики
| Target Species | Human |
| Specificity | CD305 |
| Other Names | CD305, LAIR1 |
| Fluorochrome | PE |
| Regulatory Status | ASR |
| Size | 1 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | NKTA255 |
| Isotype | IgG1 Mouse |
