The CD23 antigen (also called B6) is a 45 kDa transmembrane glycoprotein associated with MHC Class II antigen, which belongs to the C-type lectin family. CD23 is the low affinity receptor for IgE (FcεRII). CD23 antigen is expressed on B lymphocytes, monocytes and follicular dendritic cells (FDC). Expression of CD23 by B lymphocytes is up-regulated following mitogen or antigen activation. Soluble forms of CD23 are generated by proteolytic cleavage of the membrane molecule.
Технические характеристики
| Target Species | Human |
| Specificity | CD23 |
| Other Names | B6, CD23, FceRII, FcεRII, gp50-45, Low affinity IgE receptor |
| Fluorochrome | PC7 |
| Regulatory Status | ASR |
| Size | 0.5 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | 9P25 |
| Isotype | IgG1 Mouse |
| Clone Description | 9P25 blocks the binding of IgE. |
