The CD20 antigen (Bp35) is an integral non-glycosylated membrane protein with four transmembrane domains. Three isoforms (33, 35 and 37 kDa) result from differential phosphorylation within the cytoplasmic domain. The CD20 molecule is present on all normal B lymphocytes from peripheral blood, lymph node, spleen, tonsil and bone marrow but is absent from plasma cells. It is expressed naturally but at low density on a subset of peripheral blood T lymphocytes.
Технические характеристики
| Target Species | Human |
| Specificity | CD20 |
| Other Names | Bp35, CD20, membrane-spanning 4-domains |
| Fluorochrome | RD1 |
| Regulatory Status | IVD, CE, Japan IVD |
| Size | 50 Tests |
| Format | Liquid |
| Flow Product Line | cyto-stat |
| Clone | H299 |
| Isotype | IgG2a Mouse |
| Cross Reactivity | African Green, Chimpanzee, Common Marmoset, Cotton-topped Tamarin, Squirrel Monkey |
