The CD20 antigen (Bp35) is an integral non-glycosylated membrane protein with four transmembrane domains. Three isoforms (33, 35 and 37 kDa) result from differential phosphorylation within the cytoplasmic domain. The CD20 molecule is present on all normal B lymphocytes from peripheral blood, lymph node, spleen, tonsil and bone marrow but is absent from plasma cells. It is expressed naturally but at low density on a subset of peripheral blood T lymphocytes. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.
Технические характеристики
| Target Species | Human |
| Specificity | CD20 |
| Other Names | Bp35, CD20, membrane-spanning 4-domains |
| Fluorochrome | Pacific Blue* |
| Regulatory Status | ASR |
| Size | 0.5 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | B9E9 |
| Isotype | IgG2a Mouse |
| Clone Description | All monoclonal antibodies directed to the extracellular domain of the CD20 molecule are likely to bind closely related epitopes. |
| Cross Reactivity | Cynomolgus Monkey, Indian Rhesus, Pigtailed Macaque, Hamadyras Baboon, Olive Baboon, Sooty Mangabey |
