The CD2 antigen (LFA-2) is a monomeric 50 kDa glycoprotein. It was formerly described as the sheep red blood cell receptor, causing T-cell rosetting, and has been identified as the ligand for CD58 (LFA-3). It is also a receptor for CD48, CD59 and CD15, which binds to the multimeric form of CD2. CD2 is present on the majority of normal human peripheral blood T lymphocytes and a high percentage of NK cells. It is also expressed by all thymocytes.
Технические характеристики
| Target Species | Human |
| Specificity | CD2 |
| Other Names | CD2, CD58 Ligand, LFA-2, Sheep red blood cell rosettes |
| Fluorochrome | APC |
| Regulatory Status | ASR |
| Size | 1 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | 39C1.5 |
| Isotype | IgG2a Rat |
| Clone Description | 39C1.5 inhibits sheep erythrocyte rosette formation. It has been used as a CD2 reference monoclonal antibody during HLDA 6 (ref 6T-CD2.7). |
| Cross Reactivity | Cynomolgus Monkey, Hamadyras Baboon, Indian Rhesus, Olive Baboon, Capuchin Monkey, Common Marmoset, Equine, Squirrel Monkey |
