The CD19 antigen (also called B4) is a type I membrane glycoprotein with a molecular weight of 95 kDa. CD19 is involved in the regulation of B lymphocyte development, activation and differentiation. This molecule is expressed on all normal B lymphocytes including pro-B lymphocytes, but is lost in maturation to plasma cells. It is also found on the surface of follicular dendritic cells, on the early cells of myelomonocytic lineage and on most stabilized B cell lines. It is not present on normal T lymphocytes, NK cells, monocytes, and granulocytes.
Технические характеристики
| Target Species | Human |
| Specificity | CD19 |
| Other Names | B4, Bgp95, CD19 |
| Fluorochrome | ECD |
| Regulatory Status | ASR |
| Size | 0.5 mL |
| Format | Liquid |
| Flow Product Line | cyto-stat |
| Clone | HD237 |
| Isotype | IgG2b Mouse |