The CD157 antigen (BST-1) is a highly glycosylated, glycosyl-phosphatidylinositol (GPI)-anchored membrane protein with a molecular weight of 43 kDa. The amino acid sequence of human BST-1 has 33% identity with CD38. As with CD38, BST-1 displays ADP ribosyl cyclase activity and facilitates pre-B cell growth. CD157 antigen is expressed on monocytes, neutrophils and all lymphoid and myeloid precursors. Its expression is restricted to certain fractions (CD44-CD25+ and CD44-CD25-) of CD3-CD4-CD8- T progenitors.
Технические характеристики
| Target Species | Human |
| Specificity | CD157 |
| Other Names | BP-3/IF7, BST-1, cADPr hydrolase 2, CD157, CD38-like, Mo5 |
| Fluorochrome | FITC |
| Regulatory Status | RUO |
| Size | 0 mg |
| Format | Liquid |
| Clone | RF3 |
| Isotype | IgG Mouse |
| Clone Description | The RF3 antibody reacts with an external epitope of BST-1 on several human cell lines including certain bone marrow stromal cell, human umbilical vein endothelial cell (HUVEC) and U937 cell lines. |
