The CD14 antigen is a glycosyl-phosphatidylinositol-linked single-chain surface membrane glycoprotein with a molecular weight of 53-55 kDa. It functions as a high affinity receptor for the complex of LipoPolySaccharide (LPS) and the LPS-Binding Protein (LBP). It is found on cells of myelomonocytic lineage. CD14 antigen is strongly expressed on monocytes, macrophages, and weakly on neutrophils. It is also weakly expressed on B lymphocytes, but is absent from T lymphocytes, NK cells, red blood cells and platelets. It is found on Langerhans cells, follicular dendritic cells and histiocytes.
Технические характеристики
| Target Species | Human |
| Specificity | CD14 |
| Other Names | CD14, LPS Receptor |
| Fluorochrome | RD1 |
| Regulatory Status | IVD, CE, Japan IVD |
| Size | 100 Tests |
| Format | Liquid |
| Flow Product Line | coulter clone |
| Clone | 322A-1 |
| Isotype | IgG2b Mouse |
| Cross Reactivity | Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Capuchin Monkey, Squirrel Monkey |
