The CD14 antigen is a glycosyl-phosphatidylinositol-linked single-chain surface membrane glycoprotein with a molecular weight of 53-55 kDa. It functions as a high affinity receptor for the complex of LipoPolySaccharide (LPS) and the LPS-Binding Protein (LBP). It is found on cells of myelomonocytic lineage. CD14 antigen is strongly expressed on monocytes, macrophages, and weakly on neutrophils. It is also weakly expressed on B lymphocytes, but is absent from T lymphocytes, NK cells, red blood cells and platelets. It is found on Langerhans cells, follicular dendritic cells and histiocytes. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.
Технические характеристики
Target Species | Human |
Specificity | CD14 |
Other Names | CD14, LPS Receptor |
Fluorochrome | APC-Alexa Fluor* 750 |
Regulatory Status | ASR |
Size | 0.5 mL |
Format | Liquid |
Flow Product Line | IOTest |
Clone | RMO52 |
Isotype | IgG2a Mouse |