CD133, also known as AC133 or PROML1, is a 5-transmembrane glycoprotein of 120kDa belonging to the prominin family. It is mainly expressed on primitive cell populations such as CD34 hematopoietic stem and progenitor cells, neural and endothelial stem cells. In association with CD309 (KDR or VEGFR-2), CD133 allows the specific detection of endothelial progenitor cells. CD133 function is unknown although a naturally occurring mutation is associated with degenerative disease in the retina of affected patients.
Технические характеристики
| Target Species | Human |
| Specificity | CD133 |
| Other Names | AC133, PROML1, prominin-like 1, hematopoietic stem cell antigen |
| Fluorochrome | APC |
| Regulatory Status | ASR |
| Size | 0.5 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | W6B3C1 |
| Isotype | IgG1 Mouse |
| Clone Description | The clone W6B3C1 was assigned to CD133 during the Seventh HLDA Workshop on Human Leukocyte Differentiation Antigens. Similarly to AC133/1 clone, it recognizes the epitope 1. |
