The CD127 antigen is the human IL-7 receptor α chain. It is a 75-80 kDa molecule. CD127 is found on normal B cell precursors but not on mature B lymphocytes. It is also expressed by the majority of T lymphocytes, a subset of monocytes and a subset of CD34+ cells. CD127 associates with CD132 (IL-2Rγ) to form the high affinity IL-7 receptor. Receptor expression is down-regulated following T cell activation. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.
Технические характеристики
| Target Species | Human |
| Specificity | CD127 |
| Other Names | CD127, IL-7 receptor alpha chain, IL-7R alpha, interleukin-7 receptor, p90 |
| Fluorochrome | APC-Alexa Fluor* 700 |
| Regulatory Status | ASR |
| Size | 0.5 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | R34.34 |
| Isotype | IgG1 Mouse |
| Clone Description | The R34.34 antibody inhibits binding of IL-7 to CD127. |
| Cross Reactivity | Indian Rhesus, Pigtailed Macaque |
