CD11c (integrin αX subunit, also known as leucocyte surface antigen p150, Axb2 and CR4) is a member of the integrin family. Like other leucocyte integrins (CD11a, CD11b, CD11d), CD11c is non-covalently associated with the β2 integrin subunit (CD18). CD11c is a transmembrane glycoprotein of 145-150 kDa, mainly expressed by monocytes, macrophages and NK cells, and to a lesser extent by granulocytes, dendritic cells and some subsets of T and B cells.
Технические характеристики
| Target Species | Human |
| Specificity | CD11c |
| Other Names | a-chain of complement receptor type 4, alphaX, C3bi, C3dg receptor, CD11c, CR4, gp150/95, integrin αX-chain, LeuCAMc |
| Fluorochrome | PC5 |
| Regulatory Status | ASR |
| Size | 1 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | BU15 |
| Isotype | IgG1 Mouse |
| Clone Description | The BU15 antibody was used as a CD11c reference mAb (ref.6) during HLDA 6. |
| Cross Reactivity | Canine |
