The CD117 antigen is the 145 kDa protooncogene c-kit. It belongs to the class III receptor tyrosine kinase family. This antigen is the receptor for the stem-cell factor (SCF) encoded by the steel locus (Steel Locus Factor «SLF»). The CD117 antigen is expressed on very few normal bone marrow cells. The majority of CD117+ marrow cells co-express CD34. CD117 is also expressed on mast cells.
Технические характеристики
Target Species | Human |
Specificity | CD117 |
Other Names | CD117, c-kit, SCF receptor, SCFR, stem cell factor receptor |
Fluorochrome | PC5 |
Regulatory Status | ASR |
Size | 1 mL |
Format | Liquid |
Flow Product Line | IOTest |
Clone | 104D2D1 |
Isotype | IgG1 Mouse |
Cross Reactivity | Bovine |