The CD10 antigen is referred to as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). It is a type II integral membrane protein of 100 kDa, identified as the human membrane-associated neutral endopeptidase (EC3.4.24.11). It is expressed on uncommitted lymphoid precursors. CD10 expression is lost as cells enter the T lineage. In the B lineage, CD10 expression is lost later in ontogeny, as cells acquire surface Ig expression. It is also expressed on activated and proliferating B cells in the germinal center, and on neutrophils as well as on bone marrow stromal cells. It is also expressed on a number of other cells of epithelial origin.
Технические характеристики
| Target Species | Human |
| Specificity | CD10 |
| Other Names | CALLA, membrane metallo-endopeptidase |
| Fluorochrome | FITC |
| Regulatory Status | ASR, Japan IVD |
| Size | 0.5 mL |
| Format | Liquid |
| Flow Product Line | cyto-stat |
| Clone | J5 |
| Isotype | IgG2a Mouse |
| Cross Reactivity | Bovine, Equine, Ovine, Mink, Guinea Pig |
