102504-100- Seahorse XF Plasma Membrane Permeabilizer. Seahorse XF Plasma Membrane Permeabilizer (PMP) is a proprietary reagent that permeabilizes intact cells in culture, circumventing the need for mitochondrial isolation. Seahorse XF PMP allows researchers to explore the biochemistry and mechanisms of mitochondrial dysfunction. Seahorse XF PMP contains one 25 µL vial of 10 µM XF PMP, sufficient for 6 full plate assays.